Pdf the protective effects of ginger on the development of. Report patofisiologi aterosklerosis please fill this form, we will try to respond as soon as possible. Pathophysiological studies have unravelled the interactions of molecular and cellular elements involved. So, you have been told you have a damaged aorta or, perhaps worse still, hardening of the cerebral arteries. Atherosclerotic plaques can undergo pathological changes such as thrombosis. Atherosclerosis has an open access mirror journal atherosclerosis.
Atherosclerosis is a chronic immunoinflammatory, fibroproliferative disease of large and mediumsized arteries fuelled by lipid 5, 12. Solving the mechanistic atherosclerosis model and application to the cohort of mayak workers. In westernized societies, it is the underlying cause of about 50% of all deaths. Atherosclerosis atau aterosklerosis adalah penyempitan dan pengerasan. Atherosclerosis society eas tahun 2011 merupakan panduan yang praktis serta. Early pathological descriptions viewed atherosclerosis as an endstage degenerative process that inevitably resulted in a generalized. Chapter 6 atherosclerosis pathology, pathogenesis, and medical management ralph g. The most commonly diet used is the westerntype diet, which contain cholate to elevate cholesterol level.
Plaque buildup causes the artery to narrow and harden. Brachial artery vasoreactivity is associated with crosssectional and longitudinal anatomical measures of atherosclerosis. Atherosclerosis, a disease of the large arteries, is the primary cause of heart disease and stroke. Damaged ldls cannot be taken up by cells and therefore remain in blood elevated levels of ldls c. A mechanistic model for atherosclerosis and its application to the. Patofisiologi molekuler aterosklerosis dan diet aterosklerosis pada tikus penulisan kajian pustaka ini dilakukan dalam rangka memenuhi salah satu syarat untuk mencapai gelar sarjana kedokteran, jurusan pendidikan dokter pada.
It has been recognized for over a century, and the understanding of its pathogenesis has undergone many changes. This is based on the fact that atherosclerosis is a chronic inflammatory. Atherosclerosis is the most common form of arteriosclerosis, which is a general term for several disorders that cause thickening and loss of elasticity in the arterial wall. Plaque is made of fatty deposits, cholesterol, and calcium. Bila atherosclerosis terjadi pada arteri yang mensuplai darah keotak a. Pathophysiology of atherosclerosis is irreversible. Forms of accelerated arteriopathies, such as restenosis following percutaneous coronary intervention with stenting and coronary transplant vasculopathy differ in pathogenesis and are discussed separately. Pathophysiology and treatment of atherosclerosis pdf. Depalma vascular surgeons commonly treat patients with the complications of atherosclerosis. Ppt coronary artery disease powerpoint presentation free. Plaque is made up of fat, cholesterol, calcium, and. Pathophysiology and treatment of atherosclerosis ncbi. Gutstein cardiovascular institute, mount sinai medical center, box 1030, one gustave l. Recent cardiovascular clinical trials have also shed more light upon the efficacy and safety of novel compounds targeting the main.
The main locations are just above the common carotid bifurcation most common site and the start of the branches from the aorta, innominate, and subclavian arteries. This theory holds that the earliest event in atherogenesis is injury to the endothelium, which. Atherosclerosis can occur in any artery in the body, from those nourishing the heart coronary arteries to those supplying the brain, intestines, kidneys, and legs. Atherosclerosis is a disease of arteries and is characterized by endothelial dysfunction, vascular inflammation, and the buildup of lipids, cholesterol, calcium, and cellular debris within the. This means the tissue supplied by the artery is cut off from its blood supply. Atherosclerosis dapat menyerang arteri pada otak, jantung, ginjal, organ vital lainnya dan ekstremitas. Atherosclerosis is also the most serious and clinically relevant form of arteriosclerosis because it causes coronary artery disease and cerebrovascular disease. Atherosclerosis is a preventable and treatable condition. Plaque narrows the vessels and slows down blood flow. Atherosclerosis is the buildup of cholesterolfilled deposits called plaque on the inner walls of arteries. Pathophysiology of coronary artery disease circulation. Jan 24, 2014 conclusion although atherosclerosis is considered a heart disease it can happen in any part of the bodies. Atherosclerosis, also known as arteriosclerotic vascular disease, is a type of arteriosclerosis.
Comparison of the atherosclerosis percentage based on risk. Atherosclerosis is the thickening and loss of elasticity of arterial walls as a result of invasion and accumulation of white blood cells and proliferation of intimal smooth muscle cells that create a fibrofatty plaque. Keadaan tersebut menyebabkan endotel vaskular secara homeostasis mengeluarkan zatzat yang. Atherosclerosis is the leading cause in majority of cases. Impaired blood flow can result in ischemia and cause symptoms such as angina or intermittent claudication.
Hubungan berbagai faktor risiko terhadap kejadian penyakit. A free powerpoint ppt presentation displayed as a flash slide show on id. Rating is available when the video has been rented. Description download patofisiologi aterosklerosis comments. Endothelial cells, leukocytes, and intimal smooth muscle cells are the major players in the development of this disease. Mean platelet volume pasien diabetes melitus tipe ii komplikasi vaskuler.
Disease of arteries blood vessels that supply nutrients to tissue a. Asymptomatic atherosclerosis pathophysiology detection and. Currently, more precise lesion classification and imaging, a better understanding of atherogenesis, and increasingly effective medical treatment before and after vascular interventions promise. Atherosclerosis is the most common arterial abnormality characterized as arteriosclerosis, which is defined by. Pathophysiological studies have unravelled the interactions of molecular and cellular elements involved in atherogenesis.
Elevated levels of ldls result in them becoming oxidized and damaged b. View sum of plos and pubmed central page views and downloads. The response to injury theory now has widespread acceptance among scientific and medical scholars. Pemahaman tentang peranan dislipidemia dalam patofisiologi aterosklerosis semakin meningkat sejak 30 tahun terakhir, dimana dari penelitian di 7 negara. Asymptomatic atherosclerosis pathophysiology detection and treatment pdf if you found this book helpful then please like, subscribe and share. Brachial artery vasoreactivity is associated with crosssectional and longitudinal anatomical measures of atherosclerosis in postmenopausal women with coronary artery disease. Atherosclerosis, chronic disease caused by the deposition of fats, cholesterol, calcium, and other substances in the innermost layer of endothelium of the large and mediumsized arteries. Powerpoint is the worlds most popular presentation software which can let you create professional pathophysiology of atherosclerosis powerpoint presentation easily and in no time.
Pdf penyakit jantung koroner pjk merupakan penyebab. Nowadays, atherosclerosis is considered a complex chronic inflammatory disease of medium and largesized arteries. Atherosclerosis is hardening of a blood vessel from a buildup of plaque. Atherosclerosis cardiovascular disorders msd manual.
Pathophysiology and clinical significance of atherosclerotic. Pathophysiology and clinical significance of atherosclerotic plaque rupture david e. Pdf patofisiologi aterosklerosis free download pdf. Atherosclerosis is a chronic condition in which arteries harden through buildup of plaques. Pathophysiology and treatment of atherosclerosis springerlink. Free fulltext pdf articles from hundreds of disciplines, all in one place. Our new crystalgraphics chart and diagram slides for powerpoint is a collection of over impressively designed datadriven chart and editable diagram s guaranteed to impress any audience. Atherosclerosis can be prevented by life style factor and home remidies by eating healthy diet. Dr geer mohammad ishaq senior assistant professor department of pharmaceutical sciences university of kashmir july 31, 2010 for the exclusive use of kashvarsity egroup members 2.
Pathophysiology of atherosclerosis powerpoint presentation. Early pathological descriptions viewed atherosclerosis as an endstage degenerative process that inevitably resulted in a generalized narrowing of the. Our understanding of the anatomy and underlying biology of coronary atherosclerosis will likely continue to evolve, driven by advances both at the laboratory bench and in the clinic. Pathophysiology of atherosclerosis causes hardening of the. Arteries are blood vessels that carry oxygenrich blood to your heart and other parts of your body. Atherosclerotic plaques can also rupture, triggering acute formation of a clot and an abrupt. Ppt coronary artery disease powerpoint presentation free to download id. Doc aterosklerosis buyung muhammad sanusi academia. There are various kinds of dietary to induced atherosclerosis in mice.
Ppt atherosclerosis powerpoint presentation free to view. Pathogenesis, genetics and experimental models ta b l e 2 genetic loci associated with coronary artery disease with odds ratio 1. This helps you give your presentation on pathophysiology of atherosclerosis in a conference, a school lecture, a business proposal, in a webinar and business and professional. Umumnya aterosklerosis diawali dengan disfungsi endotel dan inflamasi. Atherosclerosis brings together, from all sources, papers concerned with investigation on atherosclerosis, its risk factors and clinical manifestations.
Hal tersebut secara patofisiologi melibatkan lipid, thrombosis, dinding vaskuler dan selsel imun. Type vi lesions have ruptured atherosclerotic plaque with subsequent fissure formation or hematomas in the arterial lumen. Pathophysiology and treatment of atherosclerosis, netherlands heart journal, 2017, pp. The diseasecausing lesions are believed to originate from benignlooking, nonocclusive, lipidladen plaques in childhood known as fatty streaks diagram 1b. Recent years have brought a significant amount of new results in the field of atherosclerosis. Ada pula istilah fibroateroma dengan kapsula tipis thincap fibroatheroma, tcfa, yaitu. Atherosclerosis pathophysiology on the web most recent articles. Pdf hubungan patofisiologi hipertensi dan hipertensi renal.
Atherosclerosis is one of the reasons for vascular obstruction resulting in thrombotic stroke 16. Signs and symptoms, diagnosis, overview of atherosclerosis, etiology of atherosclerosis, risk factors for atherosclerosis, epidemiology of atherosclerosis, patient education in atherosclerosis, patient history, physical examination, lipid profile, blood glucose and hemoglobin a1c, ultrasonographic examination, mri and scintigraphy. Main classical risk factors for atherosclerosis include dyslipoproteinaemia, diabetes, cigarette smoking, hypertension and genetic abnormalities. Disruption of endothelium that can occur in the setting of thispathological change initiates a complicated process that. Atherosclerosis is the most common arterial abnormality. Chart and diagram slides for powerpoint beautifully designed chart and diagram s for powerpoint with visually stunning graphics and animation effects. A better understanding of the role of different lipoprotein particles in the formation of atherosclerotic plaques is now possible. Atherosclerosis is a chronic inflammatory and immune disease that affects mediumand largesize arteries and begins with thickening in the wall of artery due to accumulation of monocytes. Patofisiologi aterosklerosis atherosclerosis facebook twitter linkedin whatsapp telegram. Introduction atherosclerosis also known as arteriosclerotic vascular disease or asvd the condition in which an artery wall thickens as the result of a buildup of fatty materials such as cholesterol affecting arterial blood vessels, a chronic inflammatory response in the walls of arteries due to the accumulation of. Type of blood vessel disorder begins as soft deposits of fat that harden with age referred to as hardening of arteries involves progressive narrowing and degeneration of arteries of heart, carotid, abdomen, and extremities. Plak plague adalah deposit lemak di dalam dinding pembuluh darah. Sistem kardiovaskuler bekerja secara terusmenerus dan pada kebanyakan kasus, secara efisien. Tapi masalah dapat muncul ketika aliran darah berkurang atau tersumbat.
From the karolinska institute, center for molecular medicine, department of medicine, karolinska university hospital, stockholm. Aterosklerosis gejala, penyebab dan mengobati alodokter. Ppt coronary artery disease powerpoint presentation. Patofisiologi aterosklerosis atherosclerosis senyum. The adobe flash plugin is needed to view this content. Download as ppt, pdf, txt or read online from scribd. In lesionprone areas, atherosclerotic lesions begin to develop. Despite our quotidian familiarity with its clinical aspects, our views of the pathophysiology of coronary atherosclerosis have changed radically in the past decade. Atherosclerosis is a pathologic process that causes disease of the coronary, cerebral, and peripheral arteries and the aorta. Atherosclerosis is a chronic, inflammatory disease of the arterial wall that underlies many of the common causes of cardiovascular morbidity and mortality, including myocardial infarction mi, cerebrovascular and peripheral vascular disease. Bila pembuluh darah ke jantung tersumbat total, jantung tidak mendapatkan oksigen secara.
The degree of experimental cholesterol atherosclerosis was graded on an arbitrary scale of 0 to 4, and. Describes how lipid plaques form in the walls arteries. Leads to build up of lipids low density lipoproteins, ldls and. Arteriolosclerosis small arteries and arterioles hypertension and dm. Actually, in this latter case, it is likely your family that would be told. Diabetic retinopathy dr is a vascular disease of the retina which affects patients with diabetes mellitus. Signs and symptoms, diagnosis, overview of atherosclerosis, etiology of atherosclerosis, risk factors for atherosclerosis, epidemiology of atherosclerosis, patient education in atherosclerosis, patient history, physical examination, lipid profile, blood glucose and hemoglobin a1c, ultrasonographic examination, mri and. Early pathological descriptions viewed atherosclerosis as an endstage degenerative process that. Ppt atherosclerosis powerpoint presentation free to. Atherosclerosis is a complex process by which arteries become progressively narrowed, impairing the supply of oxygen and nutrients to tissues. Damaged ldls enter under lining of vessels and accumulate within walls of vessels often in coronary arteries which serve the. Patogenesis acs free download as powerpoint presentation. Atherosclerosis is a disease process which is triggered by sometimes subtle physical or chemical insults to the endothelial cell layer of arteries. These progressively coalesce to form atheromas, which are enlarged plaques characterized by neointimal lipids, macrophages, cellular debris, connective tissue and an overlying fibrous plaque.
Clinical sequelae of atherosclerosis are vessel narrowing with symptoms angina pectoris and acute coronary syndromes due to plaque. Common sites for the development of atherosclerosis in extracranial and intracranial arteries. Atherosclerosis is a leading cause of mortality and morbidity in the western world. Jurnal ilmiah kedokteran volume 5 nomer 1 edisi maret 2016, hal. Atherosclerosis, the principal cause of heart attack, stroke and gangrene of the extremities, is responsible for 50% of all mortality in the usa, europe and japan. Pdf the use of ginger extracts has been recently suggested to be effective for prevention of establishing.